What Is Fareston-Toremifene Citrate
Below is a MRR and PLR article in category Health Fitness -> subcategory Other.
What is Fareston (Toremifene Citrate)?
Summary:
Toremifene Citrate, sold under the brand name Fareston, is an oral selective estrogen receptor modulator (SERM) used to combat estrogen's effects in the body. It is approved in the U.S. for treating advanced breast cancer, and studies are exploring its use in preventing prostate cancer under the name Acapodene.
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About Fareston (Toremifene Citrate):
Toremifene Citrate, known by its brand name Fareston in the U.S., is an oral medication that acts as a selective estrogen receptor modulator (SERM). It’s being researched for prostate cancer prevention under the brand Acapodene.
Fareston has the chemical formula C₂₆H₂₈ClNO and each tablet contains 88.5mg of toremifene citrate. The standard dosage is 60mg once daily. Manufactured by Orion Corporation in Finland, it is distributed in the U.S. by Roberts Pharmaceutical Corporation.
Uses and Benefits:
Fareston is a recommended first-line therapy for advanced breast cancer in women, regardless of tumor type or menopausal status. Approved by the U.S. FDA for treating metastatic breast cancer in postmenopausal women, it can also help manage cholesterol issues during treatment cycles.
Fareston displays both estrogenic and antagonist properties. While it can promote estrogen, leading to gynecomastia in men, it acts as an estrogen antagonist in the pituitary and hypothalamus, boosting testosterone production.
Comparison with Nolvadex:
While Fareston shares some properties with Nolvadex, it differs significantly. It generally presents a lower risk of side effects such as stroke, pulmonary embolism, and cataracts. Its relatively lower ocular toxicity makes it appealing to individuals with eye issues, like floaters.
Side Effects:
Initial treatment may cause nausea, vomiting, fatigue, depression, lethargy, and other reactions such as dizziness and blurred vision. Though rare, serious side effects like thrombophlebitis and pulmonary embolism can occur. It's crucial for patients to consult a doctor before using Fareston.
Ongoing Research:
GTx Inc. is conducting studies on Fareston: one focusing on treating side effects of androgen deprivation therapy for advanced prostate cancer, and another on preventing prostate cancer in high-risk men with high-grade prostatic intraepithelial neoplasia (PIN). Results from these studies were anticipated in early 2008.
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