Genetic Code for Diseases Slowly Being Cracked

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Cracking the Genetic Code for Diseases


Summary

For years, scientists have been unraveling the secrets of human DNA. Recently, the focus has shifted towards identifying genetic sequences linked to diseases, providing insights into predispositions for various illnesses.

Article


March 30, 2008, New York ?" Breakthroughs in DNA scanning and mapping are revolutionizing the search for genetic sequences associated with diseases. DNA, the blueprint for human development, is central to understanding conditions like cancer, diabetes, and arthritis.

The initiative aims to identify all building blocks of human DNA?"a milestone achieved five years ago. This achievement has accelerated research, allowing scientists to explore genetic links to a range of diseases with unprecedented detail. The human genome project's success has sparked ongoing reports on these connections, facilitated by technological advancements in DNA analysis.

In February, three independent research groups simultaneously discovered distinct genetic links to prostate cancer within a single day. Not only did they identify these connections, but they also found several genetic variants related to risk. Over the past year, there have been numerous reports of discoveries linking genetics to serious diseases like cancer and diabetes, as well as less severe conditions like restless legs syndrome.

Since 2005, over 100 genetic variants linked to approximately 40 common diseases have been identified using gene mapping technology. Harvard researchers highlighted this period as a rare surge of medical discovery.

Many are curious about the practical implications of these findings. Currently, while we can identify genetic predispositions, preventing these risks remains a future goal. Experts predict treatments based on genetic discoveries are still years away.

However, there have been some tangible benefits. Research has advanced understanding of age-related macular degeneration, the leading cause of vision loss in the elderly. These insights have led to more effective treatments.

Challenges persist, though. A Texas lab likens identifying genetic links and developing treatments to finding a needle in a haystack. The human genome project spanned decades due to the complexity of DNA, where each double-helix contains countless genetic markers. Variability is vast, with an average DNA double-helix differing at about ten million points from another.

Despite these hurdles, the quest to decode the genetic basis of diseases holds promising potential for future medical advancements.

For further details, visit:
- [ABC News](http://www.abc.net.au/7.30/stories/s144410.htm)
- [MSNBC](http://www.msnbc.msn.com/id/23017210/)

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