Fareston-Toremifene Citrate Is Selective Estrogen Receptor Modulator
Below is a MRR and PLR article in category Health Fitness -> subcategory Other.
Fareston-Toremifene Citrate: A Selective Estrogen Receptor Modulator
Fareston, known chemically as Toremifene Citrate, is a Selective Estrogen Receptor Modulator (SERM) developed by GTx, Inc. in the United States. This medication is designed to inhibit the actions of estrogen in the body, providing significant benefits in cancer treatment and prevention.
Medical Uses
Fareston-Toremifene Citrate is primarily used to treat breast cancer by exerting estrogen-blocking effects in breast tissue. It also holds potential in preventing prostate cancer. Approved by the FDA for advanced (metastatic) breast cancer treatment, it effectively prevents abnormal breast tissue growth in men as well.
Composition and Mechanism
Available in oral tablet form, its active ingredients include colloidal silicon dioxide, starch, povidone, lactose, magnesium stearate, sodium starch glycolate, and microcrystalline cellulose. The chemical formula is C26H28ClNO. Fareston works as an estrogen antagonist in the hypothalamus and pituitary gland, helping to increase testosterone levels.
Comparison with Nolvadex
Fareston is often compared to Nolvadex, another SERM, but it has distinct advantages. Fareston generally causes fewer side effects and lowers the risk of serious conditions like cataracts, stroke, and pulmonary embolism. Unlike Nolvadex, Fareston has a greater ability to increase luteinizing hormone (LH) levels, making it a popular choice among bodybuilders for preventing gynecomastia during steroid cycles.
Potential Side Effects
Despite its benefits, Fareston-Toremifene Citrate does have side effects. According to a North American study, it causes hot flashes in 35% of users, sweating in 20%, nausea in 14%, vaginal discharge in 13%, dizziness in 9%, edema in 5%, vomiting in 4%, and vaginal bleeding in 2%. Other possible side effects include cardiac issues, corneal problems, thrombosis, pulmonary embolism, leukopenia, fatigue, hair loss, jaundice, and depression.
Regulatory Status
Due to these side effects, the FDA has not approved Fareston-Toremifene Citrate and has issued warnings to its manufacturer, GTx, Inc., ordering a halt in production. The company is currently conducting further clinical trials to address these concerns.
In conclusion, while Fareston-Toremifene Citrate offers important therapeutic benefits, particularly in cancer treatment, ongoing research is essential to ensure its safety and efficacy.
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