Coronary Artery Disease

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Coronary Artery Disease


Coronary artery disease (CAD) develops when atheromatous plaques accumulate in the arteries, often without symptoms for years. This can lead to severe consequences, with heart attacks being the most dangerous outcome. These occur when plaques rupture, restricting blood flow to the heart and posing a significant risk of sudden death.

Disease Progression and Symptoms


CAD can vary greatly among individuals. Some people might be asymptomatic in the early stages because their blood flow isn't significantly blocked. During this phase, even a coronary angiogram might not detect the disease since the artery's lumen remains unaffected in size. Over time, however, plaques infiltrate the artery walls, eventually reducing the lumen and impeding blood circulation. Although this process is usually slow, a ruptured plaque can accelerate the disease unexpectedly.

Symptoms generally do not appear until more than 70% of an artery is blocked. At this point, the heart must work harder to receive adequate blood, leading to severe complications, including several heart attacks and angina. The term "ischemia" describes the reduced blood flow, which deprives heart cells of oxygen.

Causes and Risk Factors


Various factors contribute to the development of coronary artery disease. Smoking and obesity are common culprits, as is a deficiency in vitamin C. Genetics also play a significant role; those with a family history of heart disease are at higher risk.

Elevated levels of triglycerides and low-density lipoproteins (LDL) further increase the likelihood of developing CAD. Angina, characterized by chest pain, is a key symptom of advanced disease.

Prevention and Lifestyle Changes


Coronary artery disease is prevalent in Western countries, making it a leading cause of death in the United States. Prevention strategies include quitting smoking and reducing cholesterol intake. Maintaining a healthy weight through exercise and avoiding saturated fats is crucial. A sedentary lifestyle should be countered with regular physical activity. Additionally, ensuring adequate vitamin C intake supports heart health.

By adopting these lifestyle changes, individuals can significantly reduce their risk of developing coronary artery disease.

You can find the original non-AI version of this article here: Coronary Artery Disease.

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