Birth Control Pills Further Evaluation Is Needed

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Birth Control Pills: A Call for Further Evaluation


Summary


Ongoing research is essential to determine whether changes in Sex Hormone Binding Globulin (SHBG) induced by birth control pills are fully reversible after stopping the medication. This is crucial for understanding potential long-term effects on women's sexual, metabolic, and mental health.

Article


A recent study on birth control pills highlights potential long-term negative effects on women's sexual health, although it does not definitively prove that the pill causes sexual dysfunction in all users. The research suggests that some oral contraceptives can lower a woman’s free testosterone levels, which is concerning given that low testosterone is linked to several health issues, including sexual dysfunction.

Dr. Claudia Panzer and Dr. Irwin Goldstein from Boston University Medical Center found significantly lower scores on the Full Scale (a measure of female sexual function) and in the domain of sexual desire among women using oral contraceptives compared to those who had never used them.

The study noted increased instances of sexual pain among women taking oral contraceptives, as reported by Panzer and Goldstein, the latter serving as editor-in-chief of the Journal of Sexual Medicine, where the study was published.

Alarmingly, the study discovered that women who discontinued birth control pills had enduring increases in a protein that binds to testosterone. Panzer emphasized the need for further research to determine whether changes in SHBG caused by oral contraceptives are entirely reversible once the pills are stopped and if these changes contribute to long-term sexual, metabolic, and mental health issues.

The study involved 124 women with sexual health concerns. Half were using various birth control pills, 39 women had stopped using the pills at the study’s start, and 23 had never used them. Those who had never used the pill were slightly older (average age 36) than current and former users (average age 32).

Findings indicated that previous users of birth control pills reported more sexual dysfunction, reduced sexual desire, and increased sexual pain compared to never-users. These oral contraceptive users exhibited SHBG levels four times higher than those who had never used the pill. Although SHBG typically remains in the body for about two weeks, former users experienced a 2.5-fold reduction in SHBG levels after 106 days, yet levels remained higher than normal.

Panzer and her colleagues monitored 11 participants for over a year, observing that SHBG levels stayed elevated. This persistence could potentially lower testosterone levels, posing a problem.

Panzer cautioned that SHBG values might remain significantly elevated compared to never-users, even after stopping oral contraceptives. She emphasized that this early observation requires further evaluation.

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