Peyronie s disease and abnormally bent penis - causes symptoms and treatment options
Below is a MRR and PLR article in category Health Fitness -> subcategory Disease Illness.

Understanding Peyronie's Disease: Causes, Symptoms, and Treatment Options
Introduction
Peyronie's disease is a condition where the penis becomes abnormally bent or twisted due to the development of fibrous tissue. Here's a comprehensive look at the causes, symptoms, and potential treatments.
What is Peyronie's Disease?
Peyronie's disease involves the formation of hard, fibrous plaques within the shaft of the penis. These plaques are essentially internal scars that can sometimes accumulate calcium deposits, increasing their hardness. Known also as cavernositis or plastic induration, the condition likely arises from a chronic inflammation process.
The reduced blood flow to these thickened areas prevents them from filling and swelling like normal penile tissue. This results in a curvature toward the plaque when the penis is erect. If multiple plaques are present, more complex deformities can occur, often leading to painful erections. Men of any age can develop this condition, but it is most common around the age of 50.
Symptoms and Consequences
Key symptoms include:
- One or more small hard lumps under the skin, or an entire hardened area.
- An abnormally bent or crooked penis during an erection. While some curvature is normal, this disease can result in a pronounced bend, shaped like a banana or at an angle.
- Pain during erections due to pressure from the plaques or stretched skin.
- Difficulty or impossibility of sexual intercourse due to severe bending.
- The disease may progress slowly over months before the curve becomes noticeable.
- In certain cases, it can lead to erectile dysfunction, although sometimes it resolves on its own over several years.
Causes
The exact cause remains unknown, but several factors may contribute:
- Possibly starts with inflammation in penile tissue from infections, allergies, or autoimmune reactions.
- Systemic Lupus Erythematosus sufferers are more prone to the condition.
- Vitamin E deficiency and diabetes, which damages blood vessels.
- Certain medications like Inderal (propranolol) for high blood pressure.
- Physical trauma to the penis, possibly from vigorous sexual activity.
- Genetic predisposition might play a role.
Importantly, Peyronie's disease is not cancerous and does not increase cancer risk.
Treatment Options
Not everyone with Peyronie's disease requires treatment, as it can sometimes resolve naturally. However, for those in need, several treatment methods are available:
- Tamoxifen: May prevent plaque formation in the early stages. It's primarily used for breast cancer treatment.
- Vitamins E and B: Potentially effective in reducing pain and deformity.
- Verapamil: An injection into the plaque may reduce its size and alleviate pain, improving penile shape.
- Shock Wave Therapy: A newer method using extracorporeal shock waves, though long-term effects are still unknown.
- Surgery: Considered if the disease persists for a year without changes for at least three months. Procedures include tissue removal (Nesbitt procedure) or grafting, and in some cases, penile prosthesis insertion.
- Radiation Therapy: Results have been unpredictable and sometimes adverse.
- Traction Devices: These devices apply gentle tension to straighten the penis gradually.
Each treatment has its risks and benefits, so it's essential to consult with a healthcare provider to determine the best course of action.
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