Pertussis or Whooping Cough
Below is a MRR and PLR article in category Health Fitness -> subcategory Disease Illness.
Pertussis (Whooping Cough)
Summary:
Whooping cough, also known as pertussis, is a highly contagious disease and a leading cause of vaccine-preventable deaths. Annually, there are 30 to 50 million cases worldwide, with about 300,000 resulting in death, primarily in children under 12 months. Notably, 90% of these cases occur in developing countries.
Article:
Pertussis, commonly referred to as whooping cough, is a highly contagious bacterial disease that poses a significant health risk globally. Each year, it affects 30 to 50 million people, resulting in approximately 300,000 deaths, predominantly among infants under 12 months of age. Alarmingly, 90% of these cases occur in developing nations.
The disease has been recognized since 1578 and was first isolated in a pure culture in 1906 by scientists Octave Gengou and Jules Bordet. The complete genome of pertussis was mapped in 2002, consisting of 4,086,186 base pairs.
Initially, pertussis presents with mild respiratory symptoms like coughing, sneezing, and a runny nose, lasting one to two weeks. This stage evolves into severe coughing fits accompanied by a distinctive "whooping" sound and often leads to vomiting, increasing the risk of malnutrition. These symptoms gradually subside over one to two months. Complications can include pneumonia, encephalitis, pulmonary hypertension, and secondary bacterial infections.
Transmission occurs through airborne droplets from an infected person's respiratory secretions. Treatment involves antibiotics such as erythromycin, azithromycin, and clarithromycin, which reduce infectivity but often do not alter the disease course.
Vaccination is the most effective preventive measure. It is typically administered in combination with tetanus and diphtheria immunizations at 2, 4, and 6 months of age, with booster doses at 15 to 18 months and 4 to 6 years. In adults, whooping cough may go undiagnosed due to milder symptoms, underscoring the importance of widespread immunization.
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