Enlarged Prostate The Cause Remains A Mystery

Below is a MRR and PLR article in category Health Fitness -> subcategory Disease Illness.

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Enlarged Prostate: The Mystery of Its Causes


Summary

Every day, approximately 13,000 men in the US visit their doctors with urinary issues and learn they have an enlarged prostate. Known medically as Benign Prostatic Hyperplasia (BPH), this common and treatable condition affects many men over 65, and up to half of those in their sixties, and ninety percent in their seventies and eighties.

The Unsolved Puzzle of BPH

Despite advances in modern medicine, the exact cause of BPH remains uncertain. We have, however, enough evidence to begin unraveling this mystery. Genetic factors play a role, as men with a father or brother who had an enlarged prostate are more likely to develop BPH themselves.

One theory suggests that genetic instructions from puberty may reactivate later in life, either prompting further growth or increasing prostate cells' sensitivity to growth-promoting hormones.

Additionally, men who have their testes removed before puberty do not develop BPH, indicating a link between testicular aging and prostate enlargement. While the role of the testes isn't entirely clear, we know that men produce both testosterone and small amounts of estrogen throughout their lives. As men age, testosterone levels decline more than estrogen levels, possibly promoting other hormones responsible for cell growth.

Hormonal Theories

While the estrogen theory has been debated, linking it to pre-puberty testis removal remains challenging. A more credible theory involves the hormone dihydrotestosterone (DHT). DHT is crucial for the development of sex organs during pregnancy and puberty, responsible for traits like facial hair and a deeper voice. It is derived from testosterone and plays a role in prostate growth.

Even though testosterone levels drop with age, the body continues to produce DHT, which accumulates in the prostate, encouraging further growth. Men unable to produce DHT typically do not develop an enlarged prostate.

Conclusion

Research continues to uncover the exact cause of BPH, strongly linked to hormonal changes from aging. While the process is not yet fully understood, scientists are making strides in solving this medical mystery.

You can find the original non-AI version of this article here: Enlarged Prostate The Cause Remains A Mystery.

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